Arise! Awake! and stop not until the goal is reached- Swami Vivekananda
Hypertrophic Cardiomyopathy is a hereditary disorder that is typically inherited in an autosomal dominant fashion with variable penetrance and expressivity. The hallmark of the disorder is myocardial hypertrophy that is inappropriate, often asymmetrical, and occurs in the absence of an obvious inciting hypertrophy stimulus. This hypertrophy can occur in any region of the left or …
Ion channels are pore forming proteins that provide pathways for the controlled movement of ions into and out of cells. Diseases caused by mutations in genes that encode ion channel subunits or regulatory proteins are reffered to as channelopathies. Arrhythmogenesis in channelopathies: The heterogeneity in expression of ion channels results in spatial and temporal heterogeneity …